Columbia’s Ph.D. in Biological Sciences prepares students for careers in academic, pharmaceutical, and biotech research. These dissertation topics span molecular genetics, neurobiology, immunology, synthetic biology, and evolutionary theory.
Epigenetic Regulation of Neural Stem Cell Differentiation
Single-Cell Transcriptomics of Tumor Microenvironments
CRISPR-Cas9 Mediated Gene Editing in Rare Genetic Disorders
Molecular Mechanisms of Synaptic Plasticity in Memory Formation
Comparative Genomics of Evolutionary Adaptations in Desert Mammals
Role of Autophagy in Neurodegenerative Disease Progression
Reconstruction of Cell Lineage Trees Using Barcoded Genomes
Decoding Protein-Protein Interaction Networks in Immune Cells
Mechanobiology of Cancer Invasion in 3D Extracellular Matrices
Transcriptomic Analysis of Zebrafish Regenerative Pathways
Synthetic Biology Circuits for Biosensing Applications
RNA Splicing Variants in Oncogene Activation Pathways
Metagenomic Profiling of Human Gut Microbiota and Diet
Modeling Stochastic Gene Expression in Embryonic Development
Impact of Circadian Rhythm Disruption on Immune Regulation
Functional Characterization of Long Non-Coding RNAs in Cancer
High-Resolution Imaging of Chromatin Dynamics in Live Cells
Neural Circuit Mapping in Mouse Models of Anxiety Disorders
Mitochondrial Genome Evolution Across Vertebrate Lineages
Role of Ion Channels in Plant Environmental Stress Responses
Evolutionary Development of Limb Patterning Genes in Tetrapods
Protein Misfolding and Aggregate Clearance Mechanisms
Computational Modeling of Morphogen Gradient Formation
Systems Biology of Cellular Aging and Senescence Pathways
Genetic Basis of Behavioral Traits in Model Organisms
Transcription Factor Networks in Stem Cell Maintenance
Immune Cell Signaling Cross-Talk in Viral Infection Response
DNA Damage Repair Pathways in Radiation-Exposed Tissues
Developmental Regulation of Organ Size in Drosophila
Cross-Species Transcriptomics of Brain Evolution
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