The PhD in Biology at MIT enables students to explore life from molecules to systems. These project ideas reflect the frontiers of biotechnology, neurobiology, and biomedical innovation — driving discoveries in health, evolution, and synthetic design.
Single-Cell Transcriptomics in Brain Development Studies
CRISPR-Based Genetic Screens for Tumor Suppressor Genes
Synthetic Biology Circuits for Targeted Cancer Therapies
Organoid Models for Studying Human Gut Microbiome Interactions
Machine Learning in Predicting Gene Regulatory Networks
Design of Biosensors for Real-Time Cellular Metabolism Monitoring
Protein Engineering for Enhanced Enzyme Specificity
Epigenetic Regulation in Stem Cell Reprogramming
Spatial Transcriptomics of Developing Embryos
Mechanobiology of Tumor Microenvironment
RNA-Seq Analysis of Neurodegenerative Disease Pathways
Comparative Genomics of Antibiotic-Resistant Bacteria
Light-Controlled Gene Expression Using Optogenetics
Imaging Mitochondrial Dynamics in Live Cells
Targeting DNA Repair Pathways for Chemotherapy Resistance
Evolutionary Systems Biology of Microbial Populations
Integrative Multi-Omics Analysis for Metabolic Disorders
Design of Cell-Free Synthetic Biology Platforms
Neuronal Circuit Mapping in Model Organisms
Bioinformatics Pipeline for Human Microbiome Classification
High-Throughput Screening for Plant Growth Regulators
Real-Time Calcium Imaging in Neuronal Activity
Design of Peptide-Based Therapeutics for Viral Infections
Stochastic Modeling of Intracellular Molecular Interactions
Structural Analysis of Membrane Proteins Using Cryo-EM
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