The PhD in Chemistry at MIT equips researchers to innovate in chemical synthesis, spectroscopy, catalysis, and materials science. These projects span computational chemistry, nanostructures, and bioorganic interfaces — aligned with global chemical research frontiers.
Design of Metal-Organic Frameworks for CO₂ Capture
Photoredox Catalysis for Stereoselective Reactions
Mechanistic Studies of Artificial Photosynthesis Pathways
Electrochemical Sensors for Real-Time Neurotransmitter Detection
Computational Modeling of Reaction Mechanisms in Enzymes
Single-Molecule Spectroscopy of DNA-Protein Interactions
Bioconjugation Strategies for Site-Specific Protein Labeling
Design of Fluorescent Probes for Live-Cell Imaging
Development of Battery Electrolytes with High Ionic Conductivity
Catalyst-Free Green Synthetic Pathways Using Mechanochemistry
Photoactivated Drug Delivery Systems for Targeted Chemotherapy
Nanozyme Design for Reactive Oxygen Species Scavenging
Multistep Flow Synthesis of Pharmaceutical Intermediates
Metal-Ligand Cooperativity in Small Molecule Activation
Dynamic Combinatorial Chemistry for Ligand Screening
Ultrafast Spectroscopy of Excited State Proton Transfer
Peptide-Based Supramolecular Assemblies for Drug Delivery
Stability Analysis of Radical Intermediates Using EPR
Chiral Catalyst Development for Asymmetric C–H Activation
Kinetic Isotope Effect in Hydrogen Transfer Reactions
Chemical Space Exploration with Machine Learning Algorithms
Artificial Enzyme Design Through Directed Evolution
Supramolecular Chemistry for Molecular Recognition Sensors
High-Resolution Cryo-EM for Structural Analysis of Enzyme Complexes
Nanoparticle-Assisted Catalysis in Aqueous Environments
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